SNPMiner

SNP Miner Trials

Unique insights from ClinicalTrials.gov by mining proteinmutations and RSids in addition to applying the HumanPhenotype Ontology

Developed by Shray Alag, The Harker School, San Jose, CA

Reference: PLOS One Publication [May 27, 2020]

Data from May 23, 2020

Details of data processed

Java SDK

The Java API for accessing HPO and MeSH terms with clinical trials.

RSids

Details of RSids across ClinicalTrials.gov:

Item Number
1 Number of unique RSids 577
2 Number of clinical trials with Rsids 377
3 Number of RSids references 814

Java SDK

Google Colab Notebook

Protein Mutation

Protein mutations found by MutationFinder across ClinicalTrials.gov:

Item Number
1 Number of unique MutationFinder mutations 966
2 Number of clinical trials with mutation 1,975
3 Number of mutation references 3,923

Java SDK

Google Colab Notebook

Data from March 2020

Details of data processed

  • Number of clincal trials: 332,418
  • HPO: nodes: 14,961, Parent-child hierarchy: 18,547, Phenotype to gene: 820,297, Unique genes: 4,312

RSids

Details of RSids across ClinicalTrials.gov:

Item Number
1 Number of unique RSids 566
2 Number of clinical trials with Rsids 368
3 Number of RSids references 798

Protein Mutation

Protein mutations found by MutationFinder across ClinicalTrials.gov:

Item Number
1 Number of unique MutationFinder mutations 962
2 Number of clinical trials with mutation 1,939
3 Number of mutation references 3,881

Data from August 2019

Details of data processed

  • Number of clincal trials: 310,880
  • HPO: nodes: 14,708, Parent-child hierarchy: 18,312, Phenotype to gene: 521,507, Unique genes: 4,073

RSids

Details of RSids across ClinicalTrials.gov:

Item Number
1 Number of unique RSids 530
2 Number of clinical trials with Rsids 340
3 Number of RSids references 739

Protein Mutation

Protein mutations found by MutationFinder across ClinicalTrials.gov:

Item Number
1 Number of unique MutationFinder mutations 903
2 Number of clinical trials with mutation 1,793
3 Number of mutation references 3,568

Amino Acids

Amino Acid